21 Celebrities Who Have Admitted to Using Ozempic or Another Weight Loss Medication

"You thought they were going to make a weight loss drug and I wasn't going to take it? You're dumb."

Anna Quintana - Author
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Published June 18 2024, 4:44 p.m. ET

Oprah, Kelly Clarkson, Claudia Oshry, and Kelly Osbourne
Source: Getty Images

Once considered taboo, more and more celebrities are coming out of the Ozempic "closet."

Some of the biggest names in Hollywood have admitted to using weight loss medication, whether it's Ozempic, Mounjaro, or Wegovy, to lose weight.

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From Oprah Winfrey to Elon Musk to Kelly Osbourne, these stars are hoping to destigmatize using weight loss medication and inspire others to pursue alternatives to diet and exercise.

Oprah Winfrey

oprah ozempic before after
Source: Getty Images

Oprah in 2022 vs. 2024.

What she said: "I now use [an unnamed weight loss drug] as I feel I need it, as a tool to manage not yo-yoing. The fact that there's a medically approved prescription for managing weight and staying healthier, in my lifetime, feels like relief, like redemption, like a gift, and not something to hide behind and once again be ridiculed for. I’m absolutely done with the shaming from other people and particularly myself." — People

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Kelly Clarkson

kelly clarkson ozempic before after
Source: Getty Images

Kelly Clarkson in 2022 vs 2024.

What she said: "Mine is a different [drug] than people assume, but I ended up having to do that too because my bloodwork got so bad... My doctor chased me for two years, and I was like, 'No, I'm afraid of it. I already have thyroid problems.' Everybody thinks it's Ozempic, but it's not. It's something else." — The Kelly Clarkson Show

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Rebel Wilson

rebel wilson ozempic before after
Source: Getty Images

Rebel Wilson in 2017 vs. 2024.

What she said: "Someone like me could have a bottomless appetite for sweets, so I think those drugs can be good." — The Sunday Times

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Whoopi Goldberg

whoopi goldberg ozempic before after
Source: Getty Images

Whoopi Goldberg in 2022 vs. 2024.

What she said: "I will tell you, I weighed almost 300 lbs. when I made [2022 film] Till. I had taken all those steroids, I was on all this stuff, and one of the things that’s helped me drop the weight was the Mounjaro. That’s what I used." — The View

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Kelly Osbourne

kelly osbourne ozempic before after
Source: Getty Images

Kelly Osbourne in 2022 vs. 2024.

What she said: "I think it's amazing. There are a million ways to lose weight, why not do it through something that's isn't as boring as working out? The people who hate on it the most are the people who are secretly doing it or pissed off that they can't afford it. Unfortunately, right now it's something that is very expensive but it eventually won't be because it actually works." — E! Online

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Sharon Osbourne

sharon osbourne ozempic before after
Source: Getty Images

Sharon Osbourne in 2022 vs. 2024.

What she said: "You can’t stay on it forever. I lost 42 pounds now and it’s just enough." — Piers Morgan Uncensored

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Mama June

What she said: "But I have noticed over the last year and a half that I’ve really put on weight... I decided to go with semaglutide a couple of months ago through my main doctor." — Instagram Live video

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Heather Gay

heather gay ozempic before after
Source: Getty Images / Bravo

What she said: “I didn’t wanna show up at another party and see all of my friends 20 pounds thinner and just be resentful... Even after being on television, writing a New York Times bestselling book, for the first time, I was being valued by my castmates, by the public in a way that I had never been valued before. And that felt, to me, sad." — The Skinny Confessions After Ozempic

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Sunny Hostin

sunny hostin ozempic before after
Source: Getty Images

Sunny Hostin in 2022 vs. 2024.

What she said: "During COVID, I gained 40. lbs. All I did was eat ... I love to cook, and I found out, I love to eat. And I was horrified about the fact that I would have to come out on air. So I also took Mounjaro." — The View

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Claudia Oshry

claudia oshry hostin ozempic before after
Source: Getty Images

Claudia in 2022 vs. 2024.

What she said: "You thought they were going to make a weight loss drug and I wasn't going to take it? You're dumb. Of course, I'm f—ing taking it." — The Toast podcast

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Lauren Manzo

What she said: "People that are already 130 lbs. and just want to lose 10 more and they want to stay on it. That, I don't respect. I understand people with diabetes need that, and I respect that. I do think this will be really helpful for people like me, who've struggled their whole lives and had not only physical but mental issues as well from their weight." — Lauren on Mounjaro per People

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Dolores Catania

dolores catania hostin ozempic before after
Source: Getty Images

Dolores in 2022 vs. 2024.

What she said: “I don’t know why because there’s no shame in it. If a doctor gives it to you, if you’re doing things right, you’re becoming healthier by losing weight. It’s a bunch of great things that come along with this... This is my high school weight. I’m not parting with it and I’m gonna be honest because it’s right." — Sherri

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Charles Barkley

charles barkley ozempic before after
Source: Getty Images

Charles in 2018 vs. 2024.

What he said: "And he says, try this drug. And I started taking Mounjaro. And I have lost 65 pounds. I started my journey at 355 pounds. I played at 250. ... I’m down to 285." — King Charles

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Gracie McGraw

gracie mcgraw ozempic before after
Source: Getty Images

Gracie in 2015 vs. 2023.

What she said: “I did use Ozempic last year, yes. I am now on a low dose of Mounjaro for my PCOS as well as working out." — Instagram

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Elon Musk

elon musk ozempic
Source: Getty Images

What he said: "Fasting + Ozempic/Wegovy + no tasty food near me." — Twitter

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Boy George

boy george ozempic
Source: Getty Images

What he said: “I have struggled with my weight most of my life, and being under public and media scrutiny doesn’t help," and called the weight-loss medication a “wonder drug." — Karma

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Darcey Silva

darcey silva ozempic before after
Source: Getty Images / Instagram

Darcey in 2022 vs. 2024.

What she said: “Just got my Ozempic shot, so excited. It’s going to be amazing and transformational. It’s gonna help curve my appetite and lose weight." — Instagram

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Jon Gosselin

jon gosselin ozempic before after

Jon Gosselin in 2018 vs. 2024.

What he said: "I feel amazing! Like, why didn’t I do this sooner?... It’s really nice because it helped me stop drinking and it helped me get my appetite under control with less eating." — Page Six

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Margaret Josephs

margaret josephs ozempic before after
Source: Getty Images

Margaret Josephs in 2021 vs. 2024.

What she said: "After menopause, it’s so hard to lose weight. And then you’re shamed for it if you’re heavy... It shuts off that food noise, my blood work is great. [Before Ozempic] I couldn’t do anything. It doesn’t matter if I was eating right or exercising so I don’t know why there’s any shame in it if it’s helpful to people." — Sherri

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Caroline Stanbury

caroline stanbury ozempic before after
Source: Getty Images / Instagram

Caroline in 2022 vs. 2024.

What she said: "After 40, we all know, it’s very, very hard to lose weight. But I met so many 40-year-old women going, ‘How have you done it?’ And I don’t want to lie to you … I used Ozempic, which I think is one of the best tools if you’re able to use it. What did Kate Moss say? ‘Nothing tastes as good as skinny feels.’ There’s something to be said for that." — Uncut and Uncensored With Caroline Stanbury

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Scott Disick

scott disick ozempic before after
Source: Getty Images / Instagram

Scott Disick in 2021 vs. 2024.

What he said: "I had no idea how horrible it was, what I was doing at night, eating those little bread things…the Hawaiian rolls. I was pounding a whole box of them a night,” he said. “I loved them. But I didn’t realize what I was doing." — Before boxes on Mounjaro were spotted in his refrigerator on The Kardashians

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